ANDREA, bishop of SAMOSATA. — He lived in the first half of the 5th century, died before 449; he took an active part in the Nestorian controversy. At the invitation of
John of Antioch, he wrote, on behalf of the Orientals, a refutation of the anathemas of St. Cyril of Alexandria, in which he sought to put the latter in contradiction with himself. This refutation has largely come down to us in the reply of St. Cyril, entitled: *Apologeticus adversus orientales episcopos*: PG 86, 315-86. Although Anastasius the Sinaite (*Hodegos*, ch. 22: PG 89, 291-94) treats A. as a «dragon full of Nestorian venom», it does not seem, from what remains of him, that he was truly Nestorian. The fragment, cited by Anastasius, of a second treatise against Cyril, which has not come down to us, can be understood in an orthodox sense. It is certain that A., after having for some time refused to subscribe to the symbol of union between St. Cyril and the Orientals (433), soon ended by returning to the party of peace, as appears from his letter to the stewards of his intransigent metropolitan, Alexander of Hierapolis (*Synodicon Casinense*, 106: PG 84, 719-20).
Of the ten letters of A. that have come down to us in Latin, in the *Synodicon Casinense* (43, 59-63, 82-90, 98-101, 106: PG 84) 8 are addressed to Alexander of Hierapolis.