ISACCO di EDESSA. – According to Giacomo di Edessa, there would have been two I. di E., one a Monophysite from the second half of the 5th century and another who subsequently became Orthodox in the time of Asclepio (520–25). In the codices, moreover, the writings of I. di E. are confused Isacco di Antiochia (v.).
The Monophysite is said to be the author of the poem of 2,136 verses about the parrot that repeated the addition: « qui crucifixus est pro nobis ». The Catholic one, on the other hand, is said to be the author of the writings defending the Synod of Chalcedon.